BIOGRAPHY
Prof. Bassam Ali is professor of Genomic Medicine at the College of Medicine, UAE University. Prof. Ali received his PhD from Cambridge University and worked for ten years at Imperial College London before joining UAEU in 2006. Prof. Ali published over 180 original articles and reviews on the cellular and molecular mechanisms of human disease as well as pharmacogenomics and precision medicine. His current research interests include: (1) Elucidation of the cellular and molecular mechanisms underlying human monogenic diseases and (2) pharmacogenomics and (3) precision medicine. Prof Ali has been awarded the 2018 Khalifa Education Award as the Distinguished University professor and the 2019 Shoman Award for Arab Scientists in Health Sciences. In addition, Prof. Ali is the winner of the UAEU Distinguished Award for Scholarship for 2014-2015 and the College of Medicine and Health Sciences Distinguished Research Award, 2010-2011. Prof Ali supervised many postgraduate and medical research students and received numerous research grants. Prof. Ali is recognized internationally and he is on the editorial boards of several leading international scientific journals including being the Deputy-Editor-in-Chief for “Human Genomics”, and an associate editor for “Frontiers in Genetics” and “Frontiers in Pediatrics”.
EDUCATION
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Doctorate Degree, Doctor of Philosophy, Biochemistry , University of Cambridge, 1994
RESEARCH AREAS
- The cellular and molecular mechanisms underlying human monogenic diseases, Pharmacogenomics and cellular trafficking in health and disease
RECENT PUBLICATIONS
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(2024). "The double whammy of ER-retention and dominant-negative effects in numerous autosomal dominant diseases: significance in disease mechanisms and therapy". Co-Authors: Gariballa, N., Mohamed, F., Badawi, S., & Ali, B. R.
. Journal of Biomedical Science. 31(1). 64
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(2024). "The Evaluation of Drugs as Potential Modulators of the Trafficking and Maturation of ACE2, the SARS-CoV-2 Receptor". Co-Authors: Alkhofash, N. F., & Ali, B. R.. Biomolecules. 14(7). 764
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(2017). "Genomic variants in the FTO gene are associated with sporadic amyotrophic lateral sclerosis in Greek patients". Co-Authors: Mitropoulos K, Merkouri Papadima E, Xiromerisiou G, Balasopoulou A, Charalampidou K, Galani V, Zafeiri KV, Dardiotis E, Ralli S, Deretzi G, John A, Others, Ali BR, Katsila T, Patrinos GP
. Human Genomics. 11. 30
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(2017). "Defect in phosphoinositide signalling through a homozygous variant in PLCB3 causes a new form of spondylometaphyseal dysplasia with corneal dystrophy". Co-Authors: Ben-Salem S, Robbins SM, Lm Sobreira N, Lyon A, Al-Shamsi AM, Islam BK, Akawi NA, John A, Thachillath P, Al Hamed S, Valle D, Ali BR, Al-Gazali L. Journal of Medical Genetics. . 10
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(2017). "Genomic Medicine Without Borders: Which Strategies Should Developing Countries Employ to Invest in Precision Medicine? A New ". Co-Authors: Mitropoulos K, Cooper DN, Mitropoulou C, Agathos S, Reichardt JKV, Al-Maskari F, Chantratita W, Wonkam A, Dandara C, Katsila T, Lopez-Correa C, Ali BR, Patrinos GP
. OMICS. 21. 11
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(2017). "Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients". Co-Authors: Chondrou V, Kolovos P, Sgourou A, Kourakli A, Pavlidaki A, Kastrinou V, John A, Symeonidis A, Ali BR, Papachatzopoulou A, Katsila T, Patrinos GP.. Human Genomics. 11. 24
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(2017). "Genetic polymorphisms of cytochrome P450-1A2 (CYP1A2) among Emiratis". Co-Authors: Al-Ahmad MM, Amir N, Dhanasekaran S, John A, Abdulrazzaq YM, Ali BR, Bastaki SMA. PLOS ONE. 12. 10
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(2017). "Studies on N-Acetyltransferase (NAT2) Genotype Relationships in Emiratis: Confirmation of the Existence of Phenotype Variation among Slow Acetylators". Co-Authors: Al-Ahmad MM, Amir N, Dhanasekaran S, John A, Abdulrazzaq YM, Ali BR, Bastaki S. Annals of Human Genetics. 18. 7
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(2017). "Pharmaceutical Chaperones and Proteostasis Regulators in the Therapy of Lysosomal Storage Disorders: Current Perspective and Future Promises". Co-Authors: Mohamed FE, Al-Gazali L, Al-Jasmi F, Ali BR. Frontiers in Pharmacology. 8. 16
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(2017). "Key Pharmacogenomic Considerations for Sickle Cell Disease Patients". Co-Authors: Kolliopoulou A, Stratopoulos A, Siamoglou S, Sgourou A, Ali BR, Papachatzopoulou A, Katsila T, Patrinos GP. OMICS. 21. 314
