Project Description

The main theme of research in our laboratory is to understand the biology of Epstein-Barr virus (EBV) and its role in the pathogenesis of EBV associated diseases, in particular, malignancies. Although the exact molecular mechanism by which EBV induces oncogenesis is not fully understood, it is generally accepted that some of the EBV-latent gene products play a central role in this process. The current project aims to investigate the role of two small EBV encoded RNAs (EBER1 and EBER2) in the pathogenesis of EBV associated diseases.