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Profiles of Doctorate Dissertations
Research Relevance and Potential Impact
Protein-protein interaction (PPI) networks provide a global picture of cellular function and
biological processes. A better understanding of PPIs could reveal the molecular mechanism
of processes leading to diseases such as cancer and diabetes which are common in the UAE.
The project has important significance to UAE as the published results in reputable journals
will put UAE at the forefront of bioinformatics innovation. The outcome of the research work is
highly encouraging and the UAE will leverage in future projects with a vision to make significant
contributions to medicine and healthcare.
Relevant Publications
• Hanna, E.M., Zaki, N.M., and Amin, A., «Detecting Protein Complexes in Protein Interaction
Networks Modeled as Gene Expression Biclusters». PLoS ONE, 10(12): e0144163, Dec. 2015
(IF: 3.234).
• Hanna, E.M., Zaki N.M., “Gene-disease association through topological and biological feature
integration”. In Proceedings of the 11th International Conference on Innovations in Information
Technology (Innovations’15), Dubai, UAE, Nov. 2015.
• Hanna, E.M., and Zaki, N.M., “Detecting protein complexes in protein interaction networks
using a ranking algorithm with a refined merging procedure”. BMC Bioinformatics, 15:204,
June 2014 (IF 3.02).
Career Aspirations
I would like to pursue an academic and research career.